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HEARTGARD® Plus The best protection against heartworms, roundworms and hookworms for dogs 23-45kg (50-100lbs) Active Constituents: 272ug ivermectin, 227mg pyrantel (as embonate salt) Expiry - May 2011 Heartworms are transmitted to dogs and puppies by mosquitoes. Without the protection of a heartworm preventive, your pet could develop heartworm disease-a potentially deadly illness. Once a dog is infected with heartworms, treatment can be difficult and expensive. In addition to heartworms, your puppy or dog is also at risk for hookworms and roundworms, intestinal parasites that can cause dangerous diseases in pets and people. That's why it is important to provide your dog or puppy with the best protection. When used as directed, HEARTGARD Plus are 100% effective in preventing heartworm disease in dogs and puppies as young as 6 weeks old. HEARTGARD Plus also treats and controls hookworms and roundworms-making it the only real-beef Chewable that prevents heartworm disease and provides broad protection against other parasites that can threaten your pet as well.